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Vaccination: Meningitis Vaccine
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Total 2911 results found since Jan 2013.
Effectiveness of the pneumococcal polysaccharide and conjugated vaccines in elderly and high-risk populations in preventing invasive pneumococcal disease: A systematic search and review of the literature
Conclusion: The results from this review indicate a reduction of IPD in elderly and high-risk populations vaccinated with PPV23 and PCV13. The protective effect may be lower in elderly individuals >80 years and in individuals with comorbidities. However, the literature is sparse and large-scale prospective studies are needed to evaluate the effectiveness of PPV23 and PCV13 vaccination in adults in protecting against IPD.
Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: Sikjaer, M., Wik, M. S., Stensholt, S. S., Hilberg, O., Lokke, A. Tags: 10.01 - Respiratory infections and bronchiectasis Source Type: research
Fight Aging! Newsletter, May 25th 2020
In conclusion, our results suggest a previously unknown mechanism whereby the canonical NF-κB cascade and a mitochondrial fission pathway interdependently regulate endothelial inflammation.
Lin28 as a Target for Nerve Regeneration
https://www.fightaging.org/archives/2020/05/lin28-as-a-target-for-nerve-regeneration/
Researchers here show that the gene Lin28 regulates axon regrowth. In mice, raised levels of Lin28 produce greater regeneration of nerve injuries. Past research has investigated Lin28 from the standpoint of producing a more general improvement in regenerative capacity. It improves mitochondri...
Source: Fight Aging! - May 24, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Proteomic Analysis and Virulence Assessment of Granulicatella adiacens Secretome
In conclusion, we unraveled the secretome of G. adiacens, an oral bacterium well-documented in infective endocarditis, but also recently shown to be involved in oral infections. Importantly, the secretome of G. adiacens comprised of a large number of putative virulence factors. Of particular importance is the finding that the G. adiacens secretome comprised of a number of “moonlighting” proteins, which in other species are shown to enhance bacterial colonization and virulence through their multifunctional roles (Pavkova et al., 2017; Graf et al., 2019). Thus, our results provide a basis for investigating th...
Source: Frontiers in cellular and infection microbiology - April 23, 2019 Category: Microbiology Source Type: research
Fight Aging! Newsletter, February 13th 2023
This study investigated whether taller Polish adults live longer than their shorter counterparts. Data on declared height were available from 848,860 individuals who died in the years 2004-2008 in Poland. To allow for the cohort effect, the Z-values were generated. Separately for both sexes, Pearson's r coefficients of correlation were calculated. Subsequently, one way ANOVA was performed.
The correlation between adult height and longevity was negative and statistically significant in both men and women. After eliminating the effects of secular trends in height, the correlation was very weak (r = -0.0044 in men and ...
Source: Fight Aging! - February 12, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Spontaneous reports of primary ovarian insufficiency after vaccination: A review of the vaccine adverse event reporting system (VAERS)
CONCLUSIONS: POI is rarely reported to VAERS. Most reports contained limited diagnostic information and were submitted after published cases of POI following HPV vaccination. Results of our review do not suggest a safety concern.PMID:36732165 | DOI:10.1016/j.vaccine.2022.12.038
Source: Vaccine - February 2, 2023 Category: Allergy & Immunology Authors: A Patricia Wodi Paige Marquez Adamma Mba-Jonas Faith Barash Kosal Nguon Pedro L Moro Source Type: research
Hospitalized patients with COPD: analysis of prior treatment
Conclusions: The application of various non-pharmacological management recommendations was unsatisfactory. Regarding the GOLD recommendations, the high rate of inappropriate maintenance treatment was mainly due to undertreatment. In Brazil, even in severe COPD cases, optimizing treatment to achieve greater benefits continues to be a challenge. Objetivo: Embora a DPOC seja uma enfermidade prevalente, ela é subtratada, e dados sobre o tratamento prévio são desconhecidos em nosso meio. Buscou-se verificar a adequação às recentes diretrizes no que se refere ao tratamento de manutenção em pacientes com DPOC antes de sua...
Source: Jornal Brasileiro de Pneumologia - July 16, 2014 Category: Respiratory Medicine Source Type: research
The Effectiveness of Disaster Risk Communication: A Systematic Review of Intervention Studies
The objectives of the interventions were to improve the health knowledge and behaviour in relation to disasters, and to decrease the incidence of negative health events. The studies were chosen on that basis, and several studies reported additional outcomes that were outside the scope of this review. The knowledge, behaviour and incidence outcomes are described in detail in Appendix 3 (characteristics and results of included studies).
Results of Individual Studies
1 Effect of Risk Communication Interventions to Promote Disaster Mitigation and Preparedness
1.1 Communication to Promote Mitigation and Preparedness for Infec...
Source: PLOS Currents Disasters - August 22, 2014 Category: Global & Universal Authors: dtbradley Source Type: research
Pneumococcal conjugate vaccine and changing epidemiology of childhood bacterial meningitis.
PMID: 25475554 [PubMed - as supplied by publisher]
Source: Jornal de Pediatria - December 1, 2014 Category: Pediatrics Authors: Madhi SA Tags: J Pediatr (Rio J) Source Type: research
Antibody persistence following meningococcal C conjugate vaccination in children and adolescents infected with human immunodeficiency virus.
CONCLUSION: Seroprotection at 12-18 months after single dose of MCC was low for both groups, and higher among individuals who presented baseline immunity. Among HIVI, vaccine should be administered after UVL is achieved.
PMID: 28441513 [PubMed - as supplied by publisher]
Source: Jornal de Pediatria - April 22, 2017 Category: Pediatrics Authors: Frota ACC, Harrison LH, Ferreira B, Menna-Barreto D, Castro RBN, Silva GPD, Oliveira RH, Abreu TF, Milagres LG, Hofer CB Tags: J Pediatr (Rio J) Source Type: research
Theoretical pneumococcal vaccine coverage: analysis of serotypes isolated from inpatients at a tertiary care hospital
Conclusions: If the patients in this sample had been previously vaccinated with PCV13 plus PPV23, theoretically, 50.8% of the cases of invasive pneumococcal disease that required hospital admission could potentially have been prevented. Invasive pneumococcal disease should be prevented by vaccination not only of children and the elderly but also of adults in their economically productive years, so as to reduce the socioeconomic costs, morbidity, and mortality s till associated with the disease, especially in underdeveloped countries.RESUMO Objetivo: Avaliar os sorotipos de Streptococcus pneumoniae isolados de uma popula ç...
Source: Jornal Brasileiro de Pneumologia - December 12, 2018 Category: Respiratory Medicine Source Type: research
The Role of Media and the Internet on Vaccine Adverse Event Reporting: A Case Study of Human Papillomavirus Vaccination
Conclusions: We demonstrate that media coverage and Internet search activity, in particular, may promote increased adverse event reporting. Public health officials who have long recognized the importance of proactive engagement with news media must now consider strategies for meaningful participation in Internet discussions.
Source: Journal of Adolescent Health - November 18, 2013 Category: Child Development Authors: Jan M. Eberth, Kimberly N. Kline, David A. Moskowitz, Jane R. Montealegre, Michael E. Scheurer Tags: Original Articles Source Type: research
Prophylactic antibiotics for preventing pneumococcal infection in children with sickle cell disease
CONCLUSIONS: The evidence examined was determined to be of low certainty and suggests that prophylactic penicillin significantly reduces risk of pneumococcal infection in children with homozygous SCD, and is associated with minimal adverse reactions. Further research may help to determine the ideal age to safely withdraw penicillin.PMID:33724440 | DOI:10.1002/14651858.CD003427.pub5
Source: Cochrane Database of Systematic Reviews - March 16, 2021 Category: General Medicine Authors: Angela E Rankine-Mullings Shirley Owusu-Ofori Source Type: research
Influenza Vaccination and Risk of Ischemic Stroke: A Population-Based Case-Control Study
DISCUSSION: Results are compatible with a moderate protective effect of influenza vaccine on IS appearing early after vaccination. The finding that a reduced risk was also observed in pre-epidemic periods suggests that either the "protection" is not totally linked to prevention of influenza infection, or it may be partly explained by unmeasured confounding factors.PMID:36240087 | DOI:10.1212/WNL.0000000000201123
Source: Cancer Control - October 14, 2022 Category: Cancer & Oncology Authors: Sara Rodr íguez-Martín Diana Barreira-Hern ández Miguel Gil Alberto Garc ía-Lledó Laura Izquierdo-Esteban Francisco Jose De Abajo Source Type: research
Prophylactic antibiotics for preventing pneumococcal infection in children with sickle cell disease.
CONCLUSIONS: Prophylactic penicillin significantly reduces risk of pneumococcal infection in children with homozygous sickle cell disease, and is associated with minimal adverse reactions. Further research may help to determine the ideal age to safely withdraw penicillin.
PMID: 25375222 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - November 6, 2014 Category: Journals (General) Authors: Hirst C, Owusu-Ofori S Tags: Cochrane Database Syst Rev Source Type: research
